山东第一医科大学高层次拔尖人才，医学人工智能与大数据学院教授、转化基因组学课题组长，山东省泰山学者青年专家，国家青年人才项目评审。博士毕业于中国科学院上海生命科学学院。曾任职于美国南加州大学、费城儿童医院。目前主要从事人类遗传疾病和生物信息方向的研究，代表文章以第一作者或通讯作者发表在Cell Research, Nature Communications, The Innovation, Journal of the National Cancer Institute (两篇) 和 Journal of Allergy and Clinical Immunology (三篇)。
代表性论文
(1) Xiao Chang*, Michael March, Frank Mentch, Huiqi Qu, Yichuan Liu, Joseph Glessner, Patrick Sleiman, Hakon Hakonarson*; Genetic architecture of asthma in African American Patients; Journal of Allergy and Clinical Immunology, 2022 Sep 8. (期刊论文；IF=14.2)
(2) Xiao Chang, Yichuan Liu, Joseph Glessner, Cuiping Hou, Huiqi Qu, Kenny Nguyen, Patrick Sleiman, Lobin Lee, Sharon J Diskin, John M Maris, Hakon Hakonarson*; Identification of Mitochondrial DNA Variants Associated With Risk of Neuroblastoma, JNCI: Journal of the National Cancer Institute, 2022, 114(6): 910-913. (期刊论文；IF=10.3)
(3) Xiao Chang, Michael March, Frank Mentch, Kenny Nguyen, Joseph Glessner, Huiqi Qu, Yichuan Liu, Glen Furuta, Seema Aceves, Nirmala Gonsalves, Kari Nadeau, Antonella Cianferoni, Jonathan Spergel, Patrick Sleiman, Hakon Hakonarson*; A genome-wide association meta-analysis identifies new eosinophilic esophagitis loci, Journal of Allergy and Clinical Immunology, 2022, 149(3): 988-998. (期刊论文； IF=14.2)
(4) Xiao Chang; Marina Bakay; Yichuan Liu; Joseph Glessner; Komal S Rathi; Cuiping Hou; Huiqi Qu; Zalman Vaksman; Kenny Nguyen; Patrick M A Sleiman; Sharon J Diskin; John M Maris; Hakon Hakonarson*; Mitochondrial DNA haplogroups and susceptibility to neuroblastoma, JNCI: Journal of the National Cancer Institute, 2020, 112(12): 1259-1266. (期刊论文；IF=10.3)
(5) Stanislaw J. Gabryszewski#; Xiao Chang#; Jesse W. Dudley; Frank Mentch; Michael March; John H. Holmes; Jason Moore; Robert W. Grundmeier; Hakon Hakonarson; David A. Hill*; Unsupervised modeling and genome-wide association identify novel features of allergic march trajectories, Journal of Allergy and Clinical Immunology, 2021, 147(2): 677-685. (期刊论文；IF=14.2)
(6) Xiao Chang#, Yun Li#, Kenny Nguyen, Huiqi Qu, Yichuan Liu, Joseph Glessner, Patrick MA Sleiman, Hakon Hakonarson*; Genetic correlations between COVID-19 and a variety of traits and diseases, The Innovation, 2021, 2(2): 100112. (期刊论文；IF=32.1)
(7) Xiao Chang; Yan Zhao; Cuiping Hou; Joseph Glessner; Lee McDaniel; Maura A. Diamond; Kelly Thomas; Jin Li; Zhi Wei; Yichuan Liu; Yiran Guo; Frank D. Mentch; Haijun Qiu; Cecilia Kim; Perry Evans; Zalman Vaksman; Sharon J. Diskin; Edward F. Attiyeh; Patrick Sleiman; John M. Maris*; Hakon Hakonarson*; Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk, Nature Communications, 2017, 8(1): 1-7. (期刊论文；IF=16.6)
(8) Yi Zhong#; Xiao Chang#; Xing-Jun Cao#; Yan Zhang; Huajun Zheng; Yongzhang Zhu; Chengsong Cai; Zelin Cui; Yunyi Zhang; Yuan-Yuan Li; Xiu-Gao Jiang; Guo-Ping Zhao; Shengyue Wang*; Yixue Li*; Rong Zeng*; Xuan Li*; Xiao-Kui Guo*; Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601, Cell Research, 2011, 21(8): 1210-1229. (期刊论文；IF=44.1)
科研项目
1. 国家自然科学基金面上项目，32270661，线粒体基因组变异影响神经母细胞瘤发病风险的遗传机制研究，2023-01至2026-12，54万元，主持
2. 山东省优秀青年科学基金项目（海外），生物信息学在儿童实体肿瘤遗传机制研究中的应用，60万元，主持
专利
1. 常啸，Genet基因调控网络分析系统，2016.06.06，中国，2016SR200934
2. Hakon Hakonarson，Patrick Sleiman，Xiao Chang，Schizophrenia-associated genetic loci identified in genome-wide association studies and methods of use thereof, 2018.10.16, 美国，14853987
